ICSI (Intracytoplasmic Sperm Injection) Cyprus

ICSI Cyprus

ICSI (intracytoplasmic sperm injection) treatment in Cyprus is widely preferred, especially in male factor infertility cases, due to its high success rates. Dr. Murat Önal and our experienced embryology team aim to make couples’ dreams of having a baby come true by using the most advanced laboratory technologies.

The ICSI method offers a more advanced fertilization technique compared to conventional IVF and provides effective results even in men with low sperm count or poor sperm quality. At our clinic, treatment planning is carried out with personalized protocols aiming for the highest success rates.

What is ICSI (Intracytoplasmic Sperm Injection)?

ICSI (Intracytoplasmic Sperm Injection) is the process of injecting a sperm cell directly into the egg using the microinjection method. In conventional IVF treatment, sperm and egg are combined in the laboratory and fertilization is awaited, while in ICSI, the best quality sperm is individually injected into each mature egg under a microscope.

This method:

Increases fertilization rates,
Is preferred especially in men with low sperm count or sperm morphology disorders,
Can also be applied in sperms obtained through surgical methods such as TESE (testicular sperm extraction).

In short, ICSI is a modern and effective assisted reproductive technology that maximizes the chance of sperm fertilizing the egg.

Who is ICSI Treatment Suitable For?

ICSI treatment in Cyprus is effectively applied in the following patient groups:

Men with low sperm count (oligozoospermia)
Cases with low sperm motility (asthenozoospermia)
Sperm morphology disorders (teratozoospermia)
Couples who could not achieve fertilization with conventional IVF
Azoospermia patients where sperm is obtained via TESE
Unexplained infertility cases
Female patients with decreased egg quality due to age

During the first evaluation consultation, Dr. Murat Önal analyzes all your tests in detail and determines the most suitable treatment method for you.

How is ICSI Treatment Performed in Cyprus?

At Dr. Murat Önal’s clinic, the ICSI treatment process is carried out with modern laboratory equipment at international standards. The general stages are as follows:

1 – Treatment Planning and Preparation

During the first consultation, a detailed infertility history of the couple is taken.
Necessary hormone tests, ultrasound, and sperm analysis are performed for both woman and man.
Based on the results, a personalized ICSI protocol is created.

2 – Ovarian Stimulation

Medication is administered to the woman for approximately 10–12 days to stimulate egg development.
Regular ultrasound monitoring is conducted at our clinic during this period.

3 – Egg Retrieval (OPU) Procedure

Mature eggs are collected in a 15–20 minute procedure under mild sedation.
On the same day, a sperm sample is collected from the man or TESE is performed.

4 – Microinjection (ICSI)

The embryologist injects the selected sperm into each egg using a micro-needle.
Fertilization rates are monitored daily.

5 – Embryo Transfer

The highest quality embryo is placed into the uterus of the prospective mother on transfer day.
The transfer procedure is painless and does not require anesthesia.

6 – Pregnancy Test

10–12 days after transfer, a blood β-HCG test is performed to determine pregnancy results.

ICSI treatment in Cyprus increases success rates through correct patient selection, an experienced embryology team, and high technology. Dr. Murat Önal personally follows your entire treatment process to provide the safest and most comfortable experience.

Are There Any Risks of ICSI Treatment?

ICSI (microinjection) treatment is generally a safe method; however, like any medical procedure, there are some risks and possible side effects:

Ovarian Hyperstimulation Syndrome (OHSS): An excessive response of the ovaries, which can be prevented with close monitoring.
Mild ovarian pain and bloating: May last for a few days after OPU.
Risk of multiple pregnancies: Increases depending on the number of embryos transferred; controlled with single embryo transfer.
Risk of miscarriage: May be higher especially in advanced age pregnancies.
Risk of genetic anomalies: Genetic risks of ICSI are not different from conventional IVF. PGT-A testing may be recommended in cases of advanced age or known genetic disease carriers.

Dr. Murat Önal explains all risks and possible complications in detail before treatment to ensure a safe and transparent treatment process.

ICSI Treatment Process in Cyprus

At our clinic, the ICSI (microinjection) treatment process is meticulously managed from planning to embryo transfer:

1 - Initial Consultation and Preparation

First online or in-person consultation is conducted.
Hormone tests, sperm analysis, and ultrasound examinations are completed.
Treatment protocol is planned according to your menstrual cycle.

2 - Ovarian Stimulation

Eggs are grown with daily hormone injections lasting approximately 10–12 days.
Development is monitored with regular ultrasound checks and blood tests.

3 - Egg Retrieval (OPU)

Mature eggs are collected in a 15–20 minute procedure under mild anesthesia.
A sperm sample is collected from the man or TESE is performed.

4 - Microinjection and Embryo Development

Selected sperms are injected into the eggs in the laboratory.
Fertilized embryos are monitored for 3–5 days.

5 - Embryo Transfer

The highest quality embryo is transferred to the uterus.
The transfer is painless and does not require anesthesia.

6 - Pregnancy Test

A pregnancy test is performed 10–12 days after the transfer.

Dr. Murat Önal and his team inform you transparently at every stage of your treatment, respond instantly to your questions, and stand by your side to achieve maximum success.

Differences Between ICSI and Conventional IVF

ICSI (microinjection) and conventional IVF (in vitro fertilization) offer different fertilization methods within the same treatment protocol. At Dr. Murat Önal’s clinic, the most appropriate method is determined based on each couple’s clinical situation.

Feature	Conventional IVF	ICSI (Microinjection)
Fertilization method	Sperm and egg are placed together in the same dish in the laboratory, and the sperm fertilizes the egg naturally.	The selected best quality sperm is directly injected into the egg under a microscope.
Indications	Female factor or unexplained infertility cases.	Male factor infertility (low sperm count, motility disorders, morphology problems) and cases with previous fertilization failure.
Success rate	Sufficient if sperm parameters are normal.	Provides high fertilization rates even if sperm parameters are poor.

Conclusion: ICSI is a more advanced technique compared to conventional IVF and is preferred especially in male factor infertility.

ICSI Success Rates in Cyprus

ICSI (microinjection) treatment in Cyprus is known for its high success rates. However, success rates vary depending on many factors:

Woman’s age and ovarian reserve
Sperm quality (count, motility, morphology)
Embryo quality
Uterine structure and endometrial condition

ICSI success rates at Dr. Murat Önal’s clinic:

Pregnancy rates in women under 35 are around 65–75%.
For patients aged 35–40, this rate is 50–60%.
In women over 40, success rates are around 30–40%.

Note: These rates may vary according to individual medical conditions. After the initial evaluation, our treatment team will share a realistic success rate with you in detail.

Embryo Transfer After ICSI Treatment in Cyprus

Embryo transfer is one of the most important stages of ICSI treatment. At our clinic, the embryo transfer process proceeds as follows:

Embryo Development Monitoring
After microinjection, fertilized eggs are monitored in the laboratory for 3–5 days.
Transferring a blastocyst (day 5 embryo) can increase pregnancy rates.
Transfer Day
The best quality embryo is selected.
Transfer is performed under ultrasound guidance using a thin catheter, a painless method that does not require anesthesia.
Rest After Transfer
Patients rest for approximately 30–45 minutes after the procedure.
Returning to normal daily activities on the same day is possible.
Pregnancy Test
A blood β-HCG test is performed 10–12 days after embryo transfer to determine pregnancy results.

Dr. Murat Önal and his team determine the embryo transfer day and the number of embryos to be transferred on a personalized basis to maximize both success rates and treatment safety.

Advantages of ICSI Treatment in Cyprus

Cyprus offers many advantages for ICSI treatment for both domestic and international patients. The main reasons to choose ICSI treatment at Dr. Murat Önal’s clinic:

High success rates: High fertilization and pregnancy rates thanks to modern laboratory equipment and an experienced embryology team.
Cost advantage: More economical treatment options compared to Europe and the UK.
Fast appointment and planning: Scheduling without waiting time, according to your convenience.
Personalized treatment protocol: Special planning and close follow-up for each patient.
Comfortable treatment process: Accommodation and transfer support can be organized by our clinic during treatment.
Legal flexibility: Some procedures, such as the number of embryo transfers, are applied more flexibly in Cyprus compared to Turkey.

Conclusion: ICSI treatment in Cyprus facilitates your journey to parenthood with advanced technology, an experienced team, and economic price advantages.

Frequently Asked Questions About ICSI (Microinjection) in Cyprus

Who is ICSI treatment suitable for in Cyprus?

It is suitable for men with low sperm count, motility, or morphology problems; couples who could not achieve fertilization with conventional IVF; and azoospermia cases where sperm is obtained via TESE.

What are the success rates of ICSI (microinjection) in Cyprus?

Depending on the woman’s age, success rates vary between 50–75%. Pregnancy chances are higher in women under 35.

Which clinics perform ICSI (microinjection) in Cyprus?

Dr. Murat Önal’s clinic has one of the most equipped laboratories in Cyprus. ICSI is also performed in various IVF centers in Nicosia and Kyrenia.

How long does ICSI (microinjection) treatment take in Cyprus?

It takes an average of 15–20 days, including initial preparation, ovarian stimulation, egg retrieval, and embryo transfer stages.

How much does ICSI (microinjection) cost in Cyprus?

For 2025, the average cost is between €2,800 and €4,000. Medication costs and additional procedures are not included in this price.

Is ICSI (microinjection) legal in Cyprus?

Yes, ICSI treatment is legally performed in Cyprus.

Is ICSI (microinjection) procedure painful in Cyprus?

No, egg retrieval is performed under sedation. The microinjection process is performed in the laboratory. The transfer procedure is painless.

How is embryo transfer done after ICSI (microinjection)?

The transfer is performed into the uterus under ultrasound guidance using a thin catheter, a painless procedure. Day 5 blastocyst transfer is generally preferred.

What is the difference between ICSI (microinjection) and conventional IVF in Cyprus?

In conventional IVF, sperm and egg are placed in the same dish, whereas in ICSI, sperm is directly injected into the egg under a microscope. ICSI is more effective in male factor infertility.

What is the recovery process after ICSI (microinjection) treatment in Cyprus?

Mild pain may occur for a few days after egg retrieval. Patients can return to daily life after the transfer.

Is ICSI (microinjection) effective in male infertility in Cyprus?

Yes, ICSI is the most preferred method especially for treating male infertility.

What is the pregnancy chance after ICSI (microinjection) treatment in Cyprus?

Success rates depend on the woman’s age and egg quality. There is a 65–75% chance of pregnancy in women under 35.

Can ICSI (microinjection) be repeated in Cyprus?

Yes, ICSI can be repeated after an unsuccessful treatment.

Which tests are done before ICSI (microinjection) treatment in Cyprus?

Hormone tests, ultrasound, and uterine evaluation are performed for the woman; sperm analysis and hormone tests, if necessary, are performed for the man.