What is Embryo Donation?
If a couple cannot conceive a baby and if it is confirmed that the man has no sperm and the woman has no egg or if the sperm and egg are unqualified to be used then it is recommended the couple have an embryo donation. In this case, a sperm sample, which is selected by the couple, is supplied from the sperm bank. At the same time the eggs are collected from an appropriate female donor, afterwards in our center these eggs and sperm are united using appropriate methods providing an average of 10 embryos, some of which are transferred to the expectant mother. The remaining embryos are frozen and kept to be used whenever the family may choose
The essential factor in embryo donation is the woman’s uterus must be healthy.
To Whom Can Egg Donation Be Applied?
- Menopause patients
- Patients in transition to menopause
- Patients over 43 years old
- Patients with recurrent IVF failure
- Patients whose eggs were detected to be of low quality in their previous IVF attempts
- Cases when an egg can’t be retrieved in an IVF attempt
- Oophorectomy cases
- Patients undergoing chemotherapy or radiotherapy
- Patients who carry a genetic or chromosomal disease
- Single women
- Patients that have azoospermia (absence of sperm) and inability to obtain sperm through micro-TESE or TESE
- Patients who have had poor results in IVF treatment due to low sperm quality
- Patients who carry a genetic disease that makes it impossible to work on embryos
- Patients who have a viral disease which cannot be cleaned out from the semen
- In cases when a serious chromosomal abnormality is detected in sperm
- In cases when the man is Rh+ and an isoimmunisation is detected in the women’s previous pregnancy because of this.
Which Tests Are Required Before The Procedure?
For women: Hemogram (blood count), Blood Type, TSH, FT4, HbsAg, AntiHIV, AntiHCV, VDRL.
Uterus x-ray (HSG)
SPERM AND EGG ARE NEEDED TO OBTAIN AN EMBRYO, THE DONATION OPTION IS USED FOR BOTH OF THEM.
Egg Donor Selection Criteria:
The guidelines set by infertility associations in Europe and America (ESHRE and ACOG) are used as a basis.
Age is an important criterion in donor selection. The recommended age range for egg donors is 21 to 35. However, due to the success-oriented work in our center we only accept donors between the ages of 21 and 30 because we believe that egg quality is higher in that range.
Routine tests are conducted for infectious diseases (Hepatitis B, Hepatitis C, HIV and syphilis) blood type and Rh.
The necessary genetic tests (Chromosome analysis, thalassemia, sickle cell anemia and cystic fibro-sis when needed) and psychiatric tests should be applied and the donor’s own health and family background should be examined in detail.
The donor must have a normal reproductive system and proof of previous pregnancy.
It is important that her blood type and physical characteristics are compatible with the recipient. Therefore, we ask our patients questions about their physical characteristics and we are very sensi-tive about obtaining similar characteristics in our donors. Hair color, eye color and skin color are im-portant features, but the patient can specify any characteristics when choosing a donor.
The recipient’s and the donor’s identities are kept confidential. The identities of the donor and the recipient are never shared due to the course of law. A confidentiality policy is taken as a basis in this matter.
Our center has the best and the most widespread donor infrastructure in Cyprus. It provides the highest quality donor eggs by means of its experienced team. It should not be forgotten that a high quality donor egg will also increase your chance of success.
There is no donor waiting list in these procedures. In other words, when we start our treatment the donor will also start the treatment. The treatments will be carried out parallel in this way.
Only fresh eggs are used in donation procedures in our center. Frozen eggs are never used.
One donor is used for each recipient couple in our clinic. We do not share eggs in our clinic. In this way, more eggs are used for each recipient enabling them to have additional and higher-quality embryos. The chance of success for the couple increases in this manner and after the transfer they may even have some embryos to freeze.
Having embryos to freeze is important for our patients. These embryos will be used if anything goes wrong during pregnancy (miscarriage or premature birth) or they can keep them until they want to conceive another child.
How are individuals chosen for sperm donation?
Sperm donors are chosen from a sperm bank. Each donor has a certificate for disease screening. The donor is chosen in accordance to the physical characteristics and blood type of the recipient. Detailed research is carried out to detect chromosome analysis (karyotype), thalassemia, cystic fibrosis and infectious diseases (hepatitis B, hepatitis C, HIV, syphilis, CMV). There is also additional information provided regarding the sperm donor such as his profession, a photograph from his childhood and a sample of his handwriting.
Process Of Pharmacological / Medical Treatment
The recipient’s intra uterine / endometrium requires a preliminary preparation for the embryo im-plantation and its attachment. A hormonal support should be provided to the mother for the baby to get attached. This part of her treatment is also arranged by us. Embryo transfer is planned when the intra uterine is ready for the baby to settle. This preliminary treatment process takes approxi-mately 15-20 days.
Sperm is needed to fertilize the eggs. The donor sperm is used at the day of egg collection from the donor. The sperm is processed in laboratory conditions for it to become optimal for the procedure and the optimum sperm is chosen for fertilization.
Fertilization, Embryo Development And Transfer
The oocyte / egg is fertilized by sperm under laboratory conditions by means of an advanced tech-nique called microinjection. Following this procedure, the development of embryos is observed in a culture medium. The transfer is performed in between the 3rd and 5th days according to the em-bryo development and status of the patient.
The number of embryos to be transferred is decided on together with the patient in reference to the health conditions of the patient, the condition of the uterus and the embryo quality.
The transfer procedure is painless, it takes approximately 10 minutes. There is no need for anes-thesia
After the procedure, we recommend our patients to rest for about 2 hours in our center.
When do the results come out? And what is our center’s success rate?
A pregnancy test should be performed 12 days after the embryo transfer. According to the result of this test, we are able to detect if the patient is pregnant or not.
Our success rates vary between 85-90% for embryo donation in our center due to the usage of fresh, high quality and large number of eggs and high quality sperm as well as due to our top-level laboratory conditions.
We want you to be one of the many happy couples whom we helped with our high pregnancy suc-cess rates.